A fused deep learning approach to transform drug repositioning

Kun Li, Jiacai Yi, Qing Ye, Xixi Yang, Long Yu, YouChao Deng, Chengkun Wu, Tingjun Hou, Dejun Jiang, Dongsheng Cao · Communications Chemistry · November 2025

This work presents a fused deep learning framework for drug repositioning. By integrating heterogeneous biomedical signals within a unified predictive architecture, the study improves prioritization of repurposing candidates and expands the applicability of deep learning to data-sparse repositioning scenarios.